Ko te Hydroxypropyl methyl cellulose HPMC, e mohiotia ana ano ko te hydroxypromellose, he ma ki te ma-kore-ma te cellulose eter paura, he granule ranei he wai matao te wairewa me te wai wera e rite ana ki te methyl cellulose.Ko te roopu Hydroxypropyl me te roopu methyl he here ether me te mowhiti huka o te cellulose te whakakotahitanga, he ahua o te cellulose kore-katote etere whakauru.He waerau hangarua, hohekore, viscoelastic e whakamahia nuitia ana hei whakahinuhinu i roto i nga mahi ophthalmology, hei whakangao, hei awhina ranei i nga rongoa waha.
1. Te tukanga whakaputa
Kraft penupenu ki te ihirangi αcellulose o 97%, pokey o roto o 720mL /g me te roa muka toharite o 2.6mm i waiwaitia i roto i te 49% NaOH otinga i 40 ℃ mō te 50 hēkona.Katahi ka peia te penupenu ki te tango i te taikaha 49% otinga NaOH ki te tiki cellulose alkali.Ko te tauwehenga taumaha o te (49% NaOH wairewa wai) ki (waahanga totoka o te penupenu) i roto i te taahiraa impregnation he 200. Ko te tauwehenga taumaha o te NaOH i roto i te cellulose alkali ki te totoka i roto i te penupenu he 1.49.Ko te cellulose alkali (20kg) ka tukuna ki roto i te reactor pehanga me te whakakorikori o roto, katahi ka whakakoruatia, ka purea ki te hauota kia tika te tango i te hāora mai i te reactor.Na, ka whakahaeretia te pāmahana i roto i te reactor i te 60 ℃ i te wa e mahia ana te whakaoho o roto.
Katahi ka taapirihia te 2.4kg dME me te whakamahana i roto i te reactor ki te 60 ℃.I muri i te tapiritanga o te dimethyl ether, ka tapirihia te methylene chloride ki te hanga i te ōwehenga molar o te methylene chloride ki te NaOH i roto i te cellulose alkaline 1.3, i tapirihia te propylene oxide ki te hanga i te tauwehenga taumaha o te propylene oxide ki te totoka i te penupenu 1.97, me te pāmahana i roto i te reactor. i whakahaeretia mai i te 60 ℃ ki te 80 ℃.Whai muri i te taapiri i te chloromethane me te propylene oxide, ka whakahaeretia te pāmahana i roto i te reactor mai i te 80 ℃ ki te 90 ℃.I tua atu, ka roa te tauhohenga mo te 20 meneti i te 90 ℃.
Ka whakahekehia te hau mai i te reactor, ka tangohia te makuku hydroxypropyl methyl cellulose i te reactor.Ko te pāmahana o te hydroxypropyl methyl cellulose he 62 ℃.Te ine i te 50% te rahi o te matūriki i roto i te tohanga rahi matūriki i runga i te taumaha i runga i te ōwehenga o te hydroxypropyl methyl cellulose ma nga kohao o te tatari e rima, he rereke te rahi o ia tuwhera.
Ko te mutunga, ko te rahi o te matūriki toharite o nga matūriki taratara he 6.2mm.Ko te maru hydroxypropyl methyl cellulose i whakaurua ki roto i te kneader biaxial tonu (KRC kneader S1, L/D = 10.2, rōrahi ā-0.12 L, tere hurihanga 150rpm) i te tere o te 10kg/hr, a ka riro mai i te pirau hydroxypropyl methyl cellulose.Ko te hua o nga inenga rite ki te whakamahi i nga mata e 5 me nga rahi tuwhera rereke, ko te rahi o te matūriki toharite he 1.4mm.Te taapiri i te 80 ℃ te wai wera ki te pirau hydroxypropyl methyl cellulose kua pirau i roto i te tank me te mana pāmahana o te koti.ko te nui o te tauwehenga taumaha o te hydroxypropyl methyl cellulose kua pirau ki te tapeke o te slurry he 0.1, ka riro mai te slurry.I whakakorikoria te slurry i te mahana 80 ℃ mo te 60 meneti.
Na, ka tukuna te slurry ki te tere hurihuri o te 0.5 RPM me te tātari pehanga hurihuri i mua i te whakamahana (nga hua BHS Sonthofen).Ko te pāmahana o te grout he 93 ℃.Whakamahia he papu ki te tuku slurry, he 0.2mpa te pehanga tuku papu.Ko te rahi o te whakatuwheratanga o te tātari pehanga hurihuri ko 80μm, a ko te waahi tātari he 0.12m2.Ko te slurry i tukuna ki te tātari pehanga hurihuri ka tātarihia ma te tātari ka huri hei keke tātari.Ko te keke tātari ka tukuna ki te 0.3mpa mamaoa me te 95 ℃ te wai wera me te tauwehenga taumaha o te 10.0 ki te wahanga totoka o te HYDROXYpropyl methyl cellulose kua horoia, ka tohua ma te tātari.
Ko te wai wera ka tukuna ma te papu i te pehanga tuku o te 0.2mpa.Whai muri i te toha wai wera, ka tukuna te mamaoa 0.3mpa.Na, i muri i te horoinga o nga hua ka tangohia mai i te mata tātari e te kirikiri ka tukuna ki waho o te miihini horoi.Ko nga hikoinga mai i te tuku slurry ki te tuku i nga hua horoi ka mahia tonutia.I te ine ma te whakamahi i te whakamaroke whakamaroke i te wera, he 52.8%.Ko nga hua i horoia i tukuna mai i te tātari pehanga hurihuri i whakamarokehia e te whakamaroke hau i te 80 ℃, ka kuru i roto i te mira Victory ki te whiwhi hydroxypropyl methyl cellulose.
2.Application
Kei te whakamahia te hua HPMC hei whakapakeke, hei whakamarara, hei here, hei whakaehunga me te whakapumau i roto i te umanga pueru.Ka whakamahia hoki i roto i te kapia waihanga, petrochemical, uku, pepa, hiako, rongoa, kai, whakapaipai me etahi atu ahumahi.
Te wa tuku: Maehe-23-2022