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Whakarāpopototanga o te hydroxypropyl methylcellulose HPMC HPMC

Ko te hydroxypropyl methyl cellulose HPMC he momo o te cellulose kore-katote whakaranu i te carxymetyl celloxymetyl whakaranuhia eter. Na te mea rereke o nga waahanga o te methoxyl ihirangi me nga ihirangi hydroxypropyl me nga waahanga rereke, me nga momo hydroxypropy. Ko te ihirangi hydroxypropyl, kei te tata atu tana mahi ki te hydroxypropyl methylcellose. Heoi, i roto i nga momo momo, ahakoa he iti noa iho o te roopu hydroxypropyr, he iti noa iho ranei te whakarewa i roto i te whakarewa o te tipuna, ko te pāmahana papamahi ranei te tino rereke i roto i te otinga wai.

1. Ko te whakarewa o te hydroxypropyl methylcellose
yublity o te hydroxypropyl methyl cellulose i roto i te wai hydroxypropyl wai ko te cellulose cellulose i whakarereketia e te praylenexide. He rite ano te cellulose i roto i te whakarewa o te wai makariri me te koretake o te wai wera. Heoi, na te roopu hydroxypropyl kua whakarerekehia, ko tona pāmahana tipu i roto i te wai wera he nui ake i te cellulose methyl. Hei tauira, ko te tirohanga o te otinga wai o te hydroxypropyl methylcellulose me te 2% methoxyl ihirangi DS = 0.73 me te hydroxypropyl ms = 000 MPA? Ko te pāmahana o te kiri ka tae ki te tata ki te 100 ° C, i te wa ko te methylcelllulose i te pāmahana kotahi noa atu ki te 55 ° C. Ko te mea he ururua i roto i te wai, kua tino pai ake. Hei tauira, ko te maakahu hydroxypropyl methylcellose (te ahua o te 0.2 ~ 0.5mm i te 20% o te otinga o te 4 ki te reanga o te wai, he ngawari te whakamahi i te wai.

Ko te whakarewatanga o te hydroxypropyl cellulise i roto i te whakarewa i te hydroxypropy cellulise i roto i te ranunga metyl i nga hua o te 2.1, me te nui o te hydroxypropyl i roto i nga hua o te 2.1. hydroxypropyl ms = 1.5 ~ 1.8 me te methoxy ds = 0.2 ~ 1.0, me te katoa o te tohu whakakapinga i runga ake i te 1.8 ka rewa i roto i te methydrous Methathic. He rewa ano i roto i nga hydrocarbons chlarnated penei i te dichlomamerch me te chloroform, me nga whakarewa tipu penei i a Acetone, isopropanol me te waipiro a Diacetone. Ko te whakarewa i roto i nga whakarewa o te tipu he pai ake i te wai-rewa.

2. Ko nga mea e pa ana ki te tirotiro i te huringa o te hydroxypropyl methylcellulose
Ko nga mea e awe ana i te hydroxypropyl methyl sellulose formciple of hydroxypropy cellulichel, penei i etahi atu cellulose etch i runga i te 2% c. Ko te tirohanga o te hua kotahi ka piki ake te piki o te kukume. Mo nga hua me nga taumaha rerekee rereke i te taua kukume, ko nga hua me nga taumaha ngota nui ake he nui ake te tirohanga. Ko tana whanaungatanga me te pāmahana he rite ki taua cellulose methyl. Ka nui haere te pāmahana, ka tiimata te tirohanga, engari ka tae ana ki te pāmahana, ka piki haere te tirohanga me te kohukohu. He teitei ake te pāmahana o te tipu o nga hua iti-tirohanga. he tiketike. Ko tana tohu kiri ko te mea anake e pa ana ki te tirohanga o te eter, engari ki te paanga whakahiato o te methoxy me te hydroxypropyl i roto i te eter me te tohu o te whakakapinga. Me tohu ko te methylcellulose methylcellistics me tana otinga he pumau i te pāmahana rūma me te kore e ngoikore te tirohanga.

3. hydroxypropyl methylcellulose waikawa me te ātete alkali
Ko te waikawa methyplcrossose te waikawa me te alkali desdroxypropyl methylcelllolose e mau ana ki te waikawa me te alkali, a kaore i pa ki te whānuitanga o te pH 2 ~ 12. Ka taea e ia te tu atu i tetahi rahinga o te waikawa marama. Pēnei i te waikawa ahua, te waikawa acetic, te waikawa citric, te waikawa phosphoric, te waikawa boric, me te waikawa te hua o te whakaiti i te whakaheke. Ko te alkali penei i te houra ngeru, kaore he wai o te wai kotash me te waiariki kaore e taea te whakapiki i te tirohanga o te otinga, katahi ka puta he ahuatanga o te heke haere i te heke mai.

4. Te whakauru o te hydroxypropyl methylcellulose
Ka taea te konatunatua o te huringa o te hydroxypropyl methyl confullose hydroxypropyl ki te whakauru i te polymer wai-rewa ki te waiho hei otinga me te tino marama. Ko enei pūhui polymer ko te polyethylene Glycol, polyvinyl acetate, polysiloxane, polymethyl vinyl siloxane, hydroxyethyl cellulose and methyl cellulose. Ko nga pūhui a te polymer taiao penei i te kaakahu i te kiri o te rabic, he mayaa gum, me era atu. Ko te methylcellosel methylcellolose ka taea te whakaranu ki te mannitol, he kowhatu ranei o te waikawa stearic, te waikawa palmitic ranei Ko enei pūhui ka taea te whakamahi hei methylcellulose. Celllosese-e hangarua ana.

5. Whakakorekore me te Whakataunga wai o te hydroxypropyl methylcellose
Ko te kowhatu o te tipu-whakarewa o te wai o te hydroxypropy me te aldehylululose e taea te tuuru me te aldehydes. Ko nga Aldehydes e hanga ana i te waikawa methylcellulose ko te momaldehyde, te adipaldehyde, me utu i te wariu ph o te otinga. Na reira, ka whakamahia te glyoxal hei kaihoko taatai ​​i roto i te hanga ahumahi. Ko te inenga o tenei momo kaihoko a te kaihoko i roto i te otinga ko te 0.2% ~ 10% o te 7% ~ 10%, ko te 3.3% ~ te mea tino pai mo Glyoxal. Ko te pāmahana maimoatanga whānui ko te 0 ~ 30 ℃, a ko te waa ko te 1 ~ 120min. Me whakahaere te tauhohenga whakawhiti-hono i raro i nga tikanga waikawa. Ko te tikanga, ko te waikawa kaha o te waro, te waikawa waro waro ranei ka taapirihia ki te whakatika i te pH o te otinga ki te 2 ~ 6, ka honoa mai a Aldehydes ki te kawe i te tauhohenga whakawhiti. . Ko nga waikawa e whakamahia ana ko te waikawa hydrochloric, te waikawa phosphoric, waikawa phosphoric, waikawa succinic ranei, he waikawa konupora ranei. Ka taea hoki e te waikawa me te aldehyde te taapiri i te wa ano ka taea te tuku i te otinga ki te whiti i roto i te waahanga pH e hiahiatia ana. Ko tenei tauhohenga e whakamahia ana i roto i te tukanga maimoatanga whakamutunga i roto i te tukanga whakarite i te Cellulose Ethes. I muri i te whakahekenga o te Eter Cellulose, he waatea ki te horoi me te horoi ki te wai i te 20 ~ 25 ° C. Ka whakamahia te hua, ka taea te taapiri i te matū Alkaline ki te otinga o te hua hei whakatika i te pH o te otinga kia tere tere ai te hua. Ko tenei tikanga e pa ana ki te otinga o te Cellulose i hangaia hei kiriata me te tukatuka i te kiriata kia pai ai te kiriata.

6. Ko te methylcellolose he ātete ki te whākōkī
Ko te methylcellulose te aukati ki te whaaia. I roto i te ao, ko te roopu o te roopu harore, he ngawari te mate o te kohinga o ia roopu i runga i te Cellulose Chain. Ko nga roopu Anhydrogluose kaore i te kaha ki te hanga i nga huka. , e pa ana ki nga matūkai mo nga microorganism. Na reira, ki te mea ka nui ake te kaha o te tohu hikareti o te cellulose, te ātete ki te horopaki o te Ether Sellulose. E korerotia ana ko te rahinga toenga o te hydroxypropyl methylcellose (DS = 1.9%, methylcelllose (DS = 1.66) ko te 3.8%, me te hydroxyethyl cellulose 1.7%. Ka kitea pea ko te kaha anti-whyzyme o te hydroxypropyl methylcellose he kaha. Na reira, ko te tuukino tino whaanui o te hydroxypropyl methylcellolose, i whakauruhia me te nuinga o te whakama, i te nuinga o nga koti-emulsion, me etahi atu, me te nuinga o te waa e hiahiatia ana te taapiri o te hunga mate. Heoi, mo te rokiroki mo te wa roa o te otinga, ko te paitini ranei o waho o te ao, ka taea te taapiri hei whakatikatika, me te kowhiringa kia rite ki nga whakaritenga whakamutunga o te otinga. Ko te FeenmmerCuric Acetate me te Manganese fluorotilicate whai hua, engari me aro ki te mahi, me te whaikorero 1 ~ 5mg o te acetate phenylmercuric ia rita o te rita o te otinga.

7. Nga taonga o te hydroxypropyl methylcelulose kiriata
Ko te whakatutukitanga o te hydroxypropyl kiriata methylcropyl kiriata tino pai, me te otinga wai, me te koretake o te raima whakarewa, a ka kore e maroke i muri i te whakamaroke. Me te kiriata uaua. He pai te ātete o te makuku ka mau tonu ki te pāmahana tiketike. Hei tauira, ko te taapiri i te kirihou hygrosscopic ka taea te whakarei ake i tana elongastation me te ngawari. Hei whakapai ake i te ngawari, te kirihou penei i te glycerin me te sorbriel te mea tino pai. Ko te kukume kotahitanga ko te 2% ~ 3%, me te nui o te kirihou he 10% ~ 20% o te cellulose eter. Mena he tiketike rawa te kiko o te kirihou, ko te ahuatanga o te haruru o Colloid Dehydration ka puta i raro i te teitei. Ko te kaha o te kiriata me te kiritora he nui ake i te kore he kirihou, ka piki ake te pikinga o te moni taapiri. Mo te hygrosscopicity o te kiriata, ka piki haere ano hoki te piki o te moni kirihou.


Te wa tuku: Feb-20-2025